מחקרים רבים כבר הראו את יעילות השימוש בביופסיה נוזלית בסרטן ריאות מסוג NSCLC.אך מה קורה בגידולים אחרים?
Circulating tumor DNA (ctDNA) in the era of personalized cancer therapy
Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review
Correlation between circulating cell‐free PIK3CA tumor DNA levels and treatment response in patients with PIK3CA‐mutated metastatic breast cancer
Clinically used breast cancer markers such as estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2 are unstable throughout tumor progression
Clonal mutational evolution in drug resistance- lessons from the PALOMA-3 study and implications for precision medicine
Genomic Assessment of Blood-derived Circulating Tumor DNA in Patients With Colorectal Cancers
Thompson et al, 2016. Clinical Cancer Research ; Villaflor et al
Liquid-Biopsy-Based Identification of EGFR T790M Mutation-Mediated Resistance to Afatinib Treatment in Patients with Advanced EGFR Mutation-Positive NSCLC, and Subsequent Response to Osimertinib